Introduction
Preparing for the OPRA (Overseas Pharmacists Readiness Assessment) exam is crucial to becoming a registered pharmacist in Australia. The syllabus of the OPRA exam is not easy, so a better understanding of the syllabus will help the candidate plan their study strategy and pass confidently. Here is elite expertise’s take on the OPRA exam syllabus, preparation advice, and study materials to help you ace the exam.
NOTE: Before discussing the OPRA exam syllabus, a quick reminder for all candidates is to refer to the APC website for a detailed explanation.
What is the OPRA Exam?
Before diving into the details of the OPRA exam, let’s take a moment to understand the broader picture of licensure exams across different countries. For those who may not know, each country has its licensure exam designed specifically for that region. Passing this exam is an important step towards becoming a registered pharmacist in that country.
For example, it’s called the PEBC exam for Canada, the PSI equivalence test for Ireland, OSPAP for the UK, and the OPRA exam for Australia (which was previously the KAPS exam, now replaced with the OPRA exam). The OPRA exam assesses the knowledge, skills, and competencies required for pharmacists to practice safely and effectively in Australia. The Overseas Pharmacist Readiness Assessment (OPRA™) exam checks if overseas-trained pharmacists have the knowledge they need in areas like biomedical, pharmaceutical, and clinical sciences to work as registered pharmacists in Australia. It ensures they meet the standards to practice safely and effectively in the country.
The OPRA™ exam is an important step in the process of provisional registration as a pharmacist in Australia. It is a computer-delivered, multiple-choice (MCQ) exam with 120 questions completed in 2.5 hours.
Also Read: A Comprehensive Guide to Pharmacist Registration in Australia
Key Notable Details to Know About the OPRA Exam
• Duration: 2.5 hours (150 minutes)
• Number of Questions: 120
• Cost: AU$2190
• Eligibility: Candidates must apply for an Eligibility Check before sitting the exam.
• Exam Format: Closed book, computer-based, delivered at approved test centres.
• Exam Structure: Each session has multiple live versions with randomly allocated questions presented in random order.
Also Read: Detail Overview About Eligibility Criteria of OPRA Exam
Overview of the OPRA Exam Syllabus
The OPRA exam deals with five basic components:
Detailed Breakdown of the OPRA Exam Syllabus
1. Biomedical sciences
It involves the study of normal and abnormal body functions, including those at the cellular level, and how diseases and disorders impact these functions. This field covers diseases and disorders’ causes (etiology) and identifies both normal and abnormal body functions.

2. Medicinal chemistry and biopharmaceutics
The drug design and development principles encompass the factors that influence and determine the materials and methods used to formulate medications.

3. Pharmacokinetics and pharmacodynamics
Factors that affect how medicines are absorbed, distributed, metabolized, and eliminated (ADME) by the body and how pathophysiological changes influence ADME and the selection of treatment options.

4. Pharmacology and toxicology
The mechanisms by which medicines function in the body, how common chemicals and poisons produce their effects, the recognition of toxic and adverse reactions, and their management.

5. Therapeutics and patient care
The clinical application of content areas 1-4 in patient care involves understanding the principles of health promotion, disease prevention, quality use of medicines, selecting medicines for special populations, and providing medicines information.

How to Prepare the OPRA Exam Syllabus for Effective OPRA Exam Preparation
1. Understand the Structure: Review the syllabus to identify key topics and their weightage.
2. Break Down the Syllabus: Divide the syllabus into sections and create a study timeline.
3. Identify Key Concepts: Focus on core concepts, definitions, and theories.
4. Create a Study Schedule: Plan study sessions, allocating more time to difficult topics.
5. Use the Syllabus as a Checklist: Track progress by checking off topics as you study them.
6. Focus on Learning Outcomes: Ensure your study aligns with the expected outcomes for each topic.
7. Use Additional Resources: Supplement with textbooks, notes, and practice questions.
8. Review Past Papers: Practice with past exam questions to test your knowledge.
9. Seek Clarification: Resolve doubts with teachers, peers, or online resources.
Resources for Mastering the OPRA Exam Syllabus
• Pharmaceutical Calculations by Howard C. Ansel – Key for mastering dosage and compounding calculations.
• Rang & Dale’s Pharmacology by James M. Ritter – Essential for understanding drug actions and mechanisms.
• Goodman & Gilman’s Pharmacological Basis of Therapeutics – Comprehensive pharmacokinetics and clinical applications reference.
• Australian Medicines Handbook (AMH) – Crucial for therapeutic decision-making in Australian clinical practice.
• Australian Therapeutic Guidelines – Evidence-based strategies for managing common conditions.
• Aulton’s Pharmaceutics – Focuses on drug formulation, manufacturing, and quality control.
• Comprehensive Pharmacy Review (CPR) – A quick reference for general pharmacy knowledge.
• Australian Pharmaceutical Formulary (APF) – Offers insights into primary healthcare and pharmacy practice.
Also Read: Detailed About OPRA Exam Reference Books
Common Challenges with the OPRA Exam Syllabus
The OPRA exam syllabus can be overwhelming due to its vast scope, confusing students about which topics to prioritize. Key challenges include:
1. Identifying Key Topics – Understanding which topics are most important and which have lesser weight can be difficult.
2. Planning the Syllabus – Students struggle to structure their study plans and manage time effectively.
3. Finding Specific References – Determining the best resources for each topic can add to the confusion.
4. Scheduling – Creating an efficient study schedule that covers all topics without feeling overwhelmed is often stressful.
Tips for To Crack OPRA EXAM for Becoming Pharmacist in Australia
1. Master Core Concepts: Focus on biochemistry, physiology, and pathophysiology, especially for asthma and cardiovascular diseases.
2. Understand ADME: Focus on how absorption, distribution, metabolism, and elimination affect drug delivery.
3. Grasp Pharmacokinetics: Know half-life, steady-state, and clearance to simplify dosage calculations.
4. Prioritize Pharmacology: Study drug interactions, mechanisms, and therapeutic effects for better decision-making.
5. Stay Updated on OTC Products: Learn about over-the-counter products and their indications.
6. Practice Scenarios: Regularly practice scenario-based questions to improve patient care skills.
7. Focus on New Topics: Attention to newly introduced syllabus areas.
These strategies will help streamline your preparation and increase exam success.
Conclusion
The OPRA exam syllabus can be huge, leaving students unsure of which topics to focus on. To help you, our pharmacy educators, Mr. Arief Mohammad and Mrs. Harika Bheemavarapu at Elite Expertise, have thoroughly reviewed essential reference books and combined their real-world pharmacy experience to create a simplified, curated OPRA exam preparation course. This course breaks down complex concepts into easy-to-understand lessons so you can focus on which is the priority to prefer in the syllabus according to the exam pattern without stress.
Join Elite Expertise for expert guidance and make your OPRA exam preparation efficient and stress-free!