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What topics are covered in the OPRA pharmacist exam 2025

Key Concepts

  • OPRA exam syllabus covers clinical, legal, and ethical pharmacy topics.
  • Designed for overseas pharmacists seeking Australian registration.
  • Tests communication, patient care, and critical thinking.
  • Includes calculation, therapeutic, and case-based questions.
  • Based on Australian pharmacist competency standards.
  • Preparation requires structured study and mock exams.
  • Law and ethics are major scoring areas in the exam.
  • Patient counselling and clinical reasoning are key skills.
  • OPRA Pharmacist exam guide 2025 outlines updated topic areas.
  • Elite Expertise offers expert-led OPRA exam preparation.

Introduction: 

For international pharmacists who wish to work in Australia as a registered pharmacist, the Overseas Pharmacist Readiness Assessment exam is the primary step. Successfully clearing this examination will make candidates eligible to work as intern pharmacists in Australia and New Zealand. It has replaced the previous Knowledge Assessment of Pharmaceutical Sciences exam from March 2024 onwards. This guide will walk you through the OPRA exam, including its full form, eligibility criteria, fees, syllabus, and a step-by-step process to become a registered pharmacist.

What Is the OPRA Pharmacist Exam and Why It Matters

Overseas Pharmacist Readiness Assessment is a test that evaluates the readiness of international pharmacists to practice safely and effectively in Australia.  This exam ensures that the professional standards of pharmacists required to work in Australia and New Zealand are met.  You are eligible for OPRA if you:
  • Hold a Bachelor of Pharmacy (BPharm), Master of Pharmacy, or Doctor of Pharmacy (PharmD) degree.
  • Candidates must provide a valid degree certificate from a recognized institution of higher education.
  • They should have an active registration with their home country or, at the very least, be eligible to be registered with the home country’s pharmacy council.
  • Candidates must complete the APC Skills Assessment and receive a successful outcome

OPRA Exam Pattern: Structure and Scoring

Mode of examination Single paper, Computer-based online exam
Number of questions 120 MCQs
duration 2.5 hours
Scoring method Rasch methodology
OPRA Pharmacist Exam Syllabus 2025 – Complete Overview The OPRA  Exam syllabus emphasizes on the clinical application of the theoretical knowledge and efficient patient care Five major content areas include:
  • Biomedical Sciences (20%),
  • Medicinal Chemistry & Biopharmaceutics (10%)
  • Pharmacokinetics &Pharmacodynamics(10%)
  • Pharmacology & Toxicology (15%)
  • Therapeutics & Patient Care (45%)

Key Competency Areas Tested in the OPRA Exam

There are five core competency areas that are assessed in the OPRA pharmacist exam. This assessment will evaluate the ability of a pharmacist to meet Australia’s professional standards. These includes:
  1. Deep knowledge of the core pharmacy subjects and skills to apply that in Professional and Ethical Practice
  2. Ability to Communicate properly and Collaborate with clinical team
  3. Ability to provide effective clinical Care
  4. Medication management 
  5. Leadership and Professional Development
At Elite Expertise, our training modules are aligned with the Australian pharmacist competency standards, ensuring that you not only pass the exam but also gain the confidence to excel in real-world pharmacy practice.

Law and Ethics – A Vital Section in the OPRA Pharmacist Exam

This section is crucial for overseas candidates as they are not well aware of the Law and ethics in the Australian healthcare system. But it is a vital part of the OPRA pharmacist exam topics. This section assesses your understanding of:
  • Australian health legislation and professional codes
  • Dispensing and controlled substance regulations
  • Ethical dilemmas and decision-making
  • Patient privacy and duty of care
Patient Care and Clinical Decision-Making Topics Explained This portion of the OPRA exam syllabus focuses on patient-centred care and evidence-based decision-making. You’ll need to demonstrate skills in:
  • Ability to think critically and make appropriate decision
  • Understand the side effects and Identifying adverse drug reactions
  • Responsibility for prescription monitoring and provide therapeutic care
  • Improve patient compliance with advising lifestyle and medication changes

Critical Thinking and Communication Skills in the OPRA Exam

Communication and decision making skills are very essential for Pharmacists in Australia. OPRA exam will evaluate the ability of patients to:
  • Understand the problems and make appropriate decisions 
  • Ability to Communicate properly with patients which showcase affection..
  • Work as a team with other healthcare professionals
  • Handle clinical cases with ease

Common Question Types You Can Expect in the OPRA Pharmacist Exam

The OPRA pharmacist exam includes multiple-choice questions (MCQs), scenario-based cases, and applied clinical reasoning problems. You’ll be tested on your ability to integrate pharmaceutical knowledge with patient care decisions. Typical question formats include:
  • Calculation problems
  • Case based scenarios and therapeutic application
  • Australian healthcare related law and ethics
  • Evaluate the counseling skills and decision making power 
Here are two sample OPRA-style questions to give you a clearer idea: Question 1: A 65-year-old male with Type 2 Diabetes and hypertension is prescribed Metformin 500 mg BD, Ramipril 5 mg OD, and Atorvastatin 20 mg OD. He reports new-onset muscle pain. What is the most likely cause and the best next step? A) Continue all medications B) Stop Metformin C) Stop Atorvastatin and check creatine kinase D) Reduce Ramipril dose (Answer: C – Atorvastatin-induced myopathy is suspected; CK test is indicated.) Question 2: A patient presents with a prescription for Morphine SR 30 mg tablets. The label instruction says “Take two tablets every 4 hours when required.” What should the pharmacist do? A) Dispense as written B) Correct the frequency and confirm with prescriber C) Reduce to one tablet every 4 hours D) Refuse to dispense without informing the prescriber (Answer: B – The dose frequency for sustained-release morphine is incorrect; clarification with the prescriber is necessary.) At Elite Expertise, our educators are consultant clinical pharmacists in Australia. They train students by bringing the real-life practice experience to every lectures. This way students are trained for exam-style questions through mock tests and detailed feedback sessions . It ensures students are fully prepared for any question type in the OPRA exam.

Expert Tips to Prepare for All OPRA Pharmacist Exam Topics

To ace the OPRA exam, consistency and smart preparation are key. Here are expert-approved strategies from Elite Expertise trainers:
  • Prepare a study schedule and start early with OPRA exam guide 2025.
  • Study materials must align with the OPRA Exam syllabus which is designed by experts in OPRA pharmacist competency standards.
  • Practicing  mock tests regularly will help to identify the weak areas.
  • Join comprehensive  training program like Elite Expertise with expert led guidance
  • Regular revision will help to focus on understanding rather than memorisation, which is very essential to pass an exam like OPRA.
These OPRA exam tips and tricks are proven to boost confidence and exam-day performance

Final Thoughts – Mastering the Syllabus for OPRA Exam Success

Passing the OPRA Exam needs proper preparation and a strategic approach. Elite Expertise is the best online educational platform for pharmacists who are preparing for various licensure exams like KAPS, OPRA, PEBC, and PSI

Frequently Asked Questions (FAQs) About the OPRA Exam

The OPRA exam is a licensing exam for overseas-trained pharmacists who want to practice in Australia.

The OPRA exam is administered by the Australian Pharmacy Council (APC).

The main OPRA exam topics include clinical pharmacy, pharmaceutical calculations, law, ethics, and communication.

You can join structured training programs such as Elite Expertise for guided preparation, mock tests, and expert mentoring.

The OPRA exam is typically conducted several times a year by the Australian Pharmacy Council (APC).

Most candidates take around 3–6 months to prepare for the OPRA exam effectively.

These standards define the professional, clinical, and ethical skills required for pharmacists to practice in Australia.

Recommended study materials include the OPRA Exam Guide 2025, the Australian Medicines Handbook (AMH), and Elite Expertise resources.

The exam is challenging but manageable with consistent study, strong conceptual understanding, and expert coaching.

After passing the OPRA exam, you proceed to the intern pharmacist registration process in Australia and gain provisional registration with AHPRA.

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Disclaimer: 

Elite Expertise is an online education platform dedicated solely to providing coaching and preparation services for the OPRA, PEBC, PSI and PTE exams. We do not offer any sponsorship or migration services. All information provided on our platform is for educational purposes only and should not be interpreted as legal or immigration advice. For inquiries regarding sponsorship, visa applications, or migration services, please consult with licensed immigration professionals or relevant authorities.


Elite Expertise is a trusted and results-driven training platform specializing in preparation for international pharmacist licensing exams. Our comprehensive courses, expert instructors, and proven methodologies have helped countless pharmacy professionals achieve their goals and succeed in competitive regulatory exams. We are proud of our strong success rate and commitment to excellence.


Elite Expertise is an independent training provider. We are not affiliated with any global pharmacy regulatory authorities or official exam-conducting bodies.

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